by Playfuls Staff |
6th February 2007
South Korean scientists have created hollow nanoscopic spheres that might be used to transport pharmaceuticals to [more] specific target organs or cell types.
The researchers at Pohang University of Science and Technology note nanoscopic capsules with surface elements that can "recognize" specific targets have been previously produced, but require pre-production methods that include a lengthy, tedious synthetic or purification procedure.
The Pohang University researchers, led by Kimoon Kim, have developed a simple approach for the direct production of polymeric nanocapsules. The researchers say their method is generally applicable to any monomers as long as they have a flat core and multiple polymerizable groups at the periphery.
Additionally, the scientists say if building blocks are chosen that are able to bind specific (bio)molecules very tightly, the surface of the capsule can be easily decorated with species that are recognized by cells, showing the transporter the way to reach its goal, such as a tumor cell.
The study is detailed in the journal Angewandte Chemie.
© 2007 UPI
